Only manufacturers need Six Sigma – Myth or Fact? It’s true that Six Sigma was first used by manufacturing giants such as Motorola and General Electric. However, a company does not need to use an assembly line or even produce a tangible product to benefit from Six Sigma. Any company that uses a simple repetitive process can put the methodology to work. Six Sigma has been applied successfully in industries as diverse as: transportation, hospitality, healthcare, retail, banking, municipal government and even fast food.